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Cerebral toxoplasmosis Category: disease = encephalitis of toxoplasma gondii, e.g. from raw meat and cat deposits sympt: focal neurology, diffuse encephalopathy, seizures, 50% has fever and/or headache CT/MRI: multiple space occupying lesions with edema, ring-shaped enhancement (in case of solitary haard on CT a lymphoma is more likely -> make MRI) LP: not indicated ther: also seronegative patients with negative CT findings: lifelong therapy! Sulfadiazine 1000 mg 4 dd po (50% dose reduction after 6-8 weeks) + Pyrimethamine 15 mg 1 dd po + Foline 15 mg 1dd po. Often allergic reaction to sulfa. Alternative: Clindamycine 1000 mg 2 dd po (or iv, e.g. in case of diarrhoea) course: improvement within 2 wk; recurrence chance of 10% Last modified: 2008-05-13 Level: physician Article visits: 527 Home Archive Edit article	NEUROWIKI NEWS Wiki closed for anonymous data entry Welcome to NeuroWiki.com >> Older articles
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