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Progressive Multifocal Leukoencephalopathy (PML)
Category: disease
Progressive Multifocal Leukoencephalopathy (PML) = viral infection caused by JC-virus (papovagroup)
sympt
: slowly progressive, focal neurology, sometimes seizures, no headache or fever
CT
: multiple hypodensities in white matter without contrast enhancement or space occupying effect
MRI
: specific hyperintense white matter abormalities (T2)
LP
: normal
PA
: demyelinisation, abnormal oligodendrocytes, JC-virus
ther
: experimental: cytarabine 2 mg/kg/dd iv during 5 days
course
: median survival 4 months
Last modified: 2007-11-21
Level: physician
Article visits: 489
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